Amphiphilic α-cyclodextrin derivatives containing residues of pharmacologically important acids

Abstract

New representatives of amphiphilic α-cyclodextrin derivatives containing residues of pharmacologically important acids both at the primary and secondary hydroxyl groups were synthesized using acyl chlorides of palmitic acid and a series of aromatic monocarboxylic acids. The acyl chloride groups were assigned to the positions C(2), C(3), or C(6) of the carbohydrate fragments of α-cyclodextrin by 13C NMR spectroscopy.