Abstract
An amperometric non-enzymatic glucose sensor of high sensitivity was developed by modification of Pt electrode with electrodeposition of Au particles on polyaniline film. The Au particles were deposited under optimum growth conditions for maximum dispersion on polymer film to achieve highly sensitive glucose sensor. The characterization of the electrode and the analytical parameters were evaluated using chronoamperometry and cyclic voltammetry techniques. The sensor showed wide linear range from 0.01-8 mM along with swift response time of less than 5 s. Moreover, a high sensitivity of 113.6 ∆A mM-1 cm-2 is obtained along with low detection limits of 0.5 ∆M. The sensor also showed high stability, reproducibility and repeatability. Furthermore, the sensor has shown high selectivity towards glucose exclusively in the presence of interferents such as sucrose, uric acid, and ascorbic acid. The practical applicability of the proposed sensor was confirmed from successful analysis of glucose in different juice samples and these results were comparable to the commercial glucose meter. Thus, our sensor stands promising non-enzymatic sensor for routine analysis of glucose.
Highlights
The detection of glucose in not limited to clinical diagnosis and used in the other fields such as pharmaceutical, food, and biotechnology.[1]
A network of PANI film is observed on PANI/Pt electrode (Fig. 1a) that provides appropriate surface area for the immobilization of the Au particles
The polyaniline film was electrodeposited on Pt electrode through in-situ electro polymerization of aniline done using CV technique at scan rate of 50 mVs–1
Summary
The detection of glucose in not limited to clinical diagnosis and used in the other fields such as pharmaceutical, food, and biotechnology.[1]. Researchers are focusing on development of an ideal glucose sensor that is highly stable, sensitive, reproducible and has a fast response.[7] All these analytical parameters can be attained in a single electrode by modification of the existing electrodes with conducting polymer-metal nanoparticles composites.[8] In such composites, the role of conducting polymer is to provide mechanical stability and high conductivity while the dispersion of metal nanoparticles is responsible for the catalytic action of the sensor. We report the development of amperometric non-enzymatic sensor with electrodeposition of Au particles on PANI film modified Pt electrode for detection of glucose. The entire scheme for preparation of the proposed sensor is shown in Scheme 1
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
