Abstract
The aim of this review was to provide an updated knowledge on the Phytochemistry and Pharmacognosy of Isolona hexaloba Engl. & Diels. A literature search was conducted to obtain information about the phytochemistry and pharmacognosy of Isolona hexaloba from various electronic databases (PubMed Central, PubMed, Science Direct and Google scholar). The scientific name of this plant species was used as a keyword for the search, along with the terms phytochemistry and pharmacognosy. The chemical structures of the Isolona hexaloba and Isolona genus naturally occurring compounds were drawn using ChemBioDraw Ultra 12.0 software package. The findings revealed that this plant is traditionally used as a purgative and in treating sores, smoke from the bark as a strained muscle relaxant, infectious and parasitic pathologies, loss of appetite, rheumatism, intestinal cramps, headache, back pains, sexual weakness. This plant is reported to possess various biological properties like antioxidant, antimicrobial, antihyperglycemic, antileishmanial and antimalarial. These properties are due to the presence of numerous naturally occurring phytochemicals like flavonoids, alkaloids, tannins, saponins, reducting sugars, coumarins, terpenes and steroids. The present mini-review revealed that Isolona hexaloba Engl. & Diels is a good candidate for Tropical Plants Screening Research program for the development of lead compounds against genetic and parasitic diseases such as the evaluation of the anthelminthic activity.
Highlights
In the Democratic Republic of the Congo (DRC), medicinal plants represent the key product for both urban and rural populations for their health care needs because the costs of conventional drugs are often unaffordable
Isolona hexaloba (I. hexaloba) Engl. & Diels is a tree of the Isolona genus Engl. which belongs to Annonaceae family, Monodoroideae sub-family and is used in DRC and Republic of the Congo as a purgative and in treating sores, and the smoke from the bark as a strained muscle relaxant
The phytochemistry screening of I. hexaloba Engl. & Diels revealed the presence of various secondary metabolites such as the alkaloids found in the root bark [10]
Summary
In the Democratic Republic of the Congo (DRC), medicinal plants represent the key product for both urban and rural populations for their health care needs because the costs of conventional drugs are often unaffordable. These medicinal plants have found to have therapeutic value which fights against major health problems [3]. & Diels is a tree of the Isolona genus Engl. Some different species of the Isolona genus (Annonaceae) have been extensively studied from both chemical and pharmacological points of view as I. cauliflora
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