Abstract

Purpose: To compare in vivo emulsification of silicone oil 1000 and 5000 centistokes (cs) after retinal detachment surgery. Design: Comparative non-interventional Retrospective study. Methods: Silicone oils from patients who underwent retinal detachment surgery were investigated using Spectrophotometer UV-Vis. Spectroscopically changes determine emulsification with the time of tamponade, inflammation, patients age and severity of retinal detachment. Results: We found significant difference on absorbance (p = 0.004) between used 1000 Centi stoke (cs) silicon oil (average wave length 2.51 nm; SD: 1.575 nm) and used 5000 cs silicon oil (average wave length 0.910 nm; SD: 0.564 nm). Conclusions: In vivo emulsification was higher in silicone oil 1000 compared to 5000 cs silicone oil after vitreoretinal tamponade 8 - 12 weeks due to retinal detachment surgery. Emulsification related to higher absorbance and lower transmittance in 1000 cs silicone oil. Inflammation may become a factor affecting this condition.

Highlights

  • Silicone oils were used in retinal detachment surgery since 1962 and had been used increasingly especially in complicated cases such as retinal detachment with severe proliferative vitreoretinopathy, giant retinal tears, proliferative diabetic retinopathy, viral retinitis and ocular trauma [1]

  • In vitro study showed that silicone oil with higher viscosity was more stable than lower viscosity, Soheilian et al found that clinically, there was no difference in complications rates between 1000 vs. 5000 cs silicone oil after retinal detachment surgery [6]

  • The purpose of this study was to compare in vivo emulsification of silicone oil and 5000 cs after retinal detachment surgery

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Summary

Introduction

Silicone oils were used in retinal detachment surgery since 1962 and had been used increasingly especially in complicated cases such as retinal detachment with severe proliferative vitreoretinopathy, giant retinal tears, proliferative diabetic retinopathy, viral retinitis and ocular trauma [1]. Emulsification is the most common complication in silicone oil tamponade [2]. Emulsification can be identified as droplet formation of a small bubble of silicone oil with or without opacification of the bubble. Silicone oil with viscosity 1000 cs is easier and faster to inject and remove but has limitation sooner to be emulsified compared to higher viscosity. In vitro study showed that silicone oil with higher viscosity was more stable than lower viscosity, Soheilian et al found that clinically, there was no difference in complications rates between 1000 vs 5000 cs silicone oil after retinal detachment surgery [6]. The purpose of this study was to compare in vivo emulsification of silicone oil and 5000 cs after retinal detachment surgery

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