Abstract

Aflatoxin M1 (AFM1) occurrence in milk and milk products has been a major concern among food scientists over the past three decades owing to its possible health risk in humans. The well-documented AFM1 associated adverse health outcomes include hepatocarcinogens, mutagens genotoxins, mutagenicity, and teratogen. The paper reviews the occurrence of AFM1 in milk, milk products, and human milk in developing and developed countries, with its safety standards of regulation. The health associated risks with AFM1 are the important methods used in detecting and reducing AFM1 in milk and other milk products are presented.

Highlights

  • Aspergillus parasiticus and Aspergillus flavus are sub-groups of fungi that produce Aflatoxins [1]

  • Aflatoxin M1 (AFM1) occurrence in milk and milk products has been a major concern among food scientists over the past three decades owing to its possible health risk in humans

  • While some studies have demonstrated that the stability of aflatoxin to heat [48], evidence from literature indicates that AFM1 can be treated using microorganisms like lactic acid bacteria (LAB), yeast Saccharomyces cerevisiae (SC), enzymes and some other techniques like ultra-violet light among others [62]

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Summary

Introduction

Aspergillus parasiticus and Aspergillus flavus are sub-groups of fungi that produce Aflatoxins [1]. When AFB1 is consumed by an animal, it’s absorbed within the alimentary canal and metabolized into aflatoxin M1 (AFM1) within the liver. This can be excreted in urine and bile but can pass into milk if the animal is lactating [5] [6]. AFM1 can even be passed into human milk when AFB1 contaminated food sub-. AFM1 in milk raises concerns on food safety because of its association with adverse health effects in humans [11]. There’s a growing incidence of the occurrence of AFM1 in milk and its products raising more concerns about food safety and public health attention across the globe [12]. The purpose of this review article is to 1) explore the occurrence of AFM1 in milk, milk products, and human milk in both developing and developed countries, and the safety standard of regulation; 2) the health associated health risks with AFM1 are examined, and 3) the important methods used in detecting and reducing AFM1 in milk and other milk products are presented

Methodology
Global Occurrences
The Occurrence of AFM1 in Breastmilk and Commercial Infant Formula
Methods of AFM1 Detection in Milk and Milk Products
Stability
Toxicity and Associated Health Risk
Treatment of AFM1 in Milk and Milk Products
Legislation or Regulation on AFM1 in Milk and Milk Product
Future Trends of AFM1 in Milk and Milk Products
Findings
Conclusion
Full Text
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