Abstract
One hundred sixty-eight strains of nine species of gram-negative bacilli isolated from patients hospitalized at Boston City Hospital in 1972 were tested for susceptibility to amoxicillin, penicillin G, ampicillin, and carbenicillin. The tests were done on heart infusion agar containing twofold dilutions of the antibiotics; a 10-3 dilution of each culture grown overnight in brain heart infusion broth was applied with the replica inoculator. By this method the activity of amoxicillin most resembled that of ampicillin; the former appeared to be slightly more active against strains of Proteus mirabilis and Serratia marcescens and somewhat less active
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