Abstract
Article title and bibliographic information The comparative efficacy of 0.12% chlorhexidine and amoxicillin to reduce the incidence and magnitude of bacteremia during third molar extractions: a prospective, blind, randomized clinical trial. Duvall NB, Fisher TD, Hensley D, Hancock RH, Vandewalle KS. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;115(6):752-63. Reviewers Marcelo Carlos Bortoluzzi, DDS, PhD, Fabio Andre Santos, DDS, PhD Purpose/Question The study purpose was to compare the incidence and magnitude of bacteremia after four third-molar extractions using three protocols: pre-procedure 0.12% chlorhexidine mouth rinse, prophylaxis regimen of 2 g of amoxicillin given orally, and placebo. Source of funding Government Funding: 59th Clinical Research Training Division, Lackland Air Force Base, Texas Type of study/Design Randomized controlled trial Level of evidence Level 2: Limited-quality, patient-oriented evidence Strength of recommendation grade Not applicable
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