Abstract

目的 评价一种新的羊膜缝合方法--连续交锁缝合,在眼表羊膜移植术中应用及其临床疗效.方法 回顾总结我院行羊膜移植术的眼表疾病患者57例(65眼),观察组26例(31眼)行连续交锁缝合,与对照组31例(34眼)行间断或单纯连续缝合者进行比较,随访时间均超过2m,观察两组羊膜脱落时间、创面上皮化时间等指标.结果 两组3w内羊膜自行脱落眼数比:观察组3/31眼明显低于对照组为15/34眼,两者之间的差别有统计学意义(P=0.018);羊膜完整存留3w以上眼数比:观察组19/22眼高于对照组6/21眼,两者之间的差别有统计学意义(P=0.044);两组2w内角膜上皮化眼数比:观察组17/28眼高于对照组12/32眼,但两者之间的差别无统计学意义(P=0.29).结论 连续交锁缝合可使羊膜紧贴眼表,防止其融解脱落,并促进眼表创面上皮化,其眼表刺激症状很小,可明显提高羊膜眼表覆盖的疗效。

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