Abstract
<p><strong>BACKGROUND: </strong>To assess the anatomical and functional results of neovagina creation with amniotic membrane.</p><p><strong>METHODS: </strong>We operated on three young women with vaginal agenesis two of whom had a diagnosis of Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome and the other mixed gonadal dysgenesis. The mean age was 29.67 years (range 28-33). A fresh amniotic membrane retrieved from a Cesarean section on the same operation date was prepared over a mould and inserted into the newly formed tunnel between the bladder and the rectum as per McIndoe technique. The patients were followed up for one year minimum. </p><p><strong>RESULTS: </strong>Mean vaginal depth achieved was 8, 10 and 7 cm (average 8.3 cm) at the 12 month follow-up clinic. Two patients expressed having satisfactory sexual life at follow-up interview. One patient who had infrequent coitus and neglected appropriate use of mould needed further follow-up in clinic and self-dilation.</p><p><strong>CONCLUSİONS: </strong>McIndoe vaginoplasty with fresh-homologous amniotic membrane is an effective low-risk procedure. It can produce good results in fairly short time span with modest demand on patient compliance and rare morbidity.</p>
Highlights
Congenital absence of the vagina is encountered with a frequency of 1 in 4.000 to 5.000 (Raga et al, 1997)
Construction of a neovagina utilising amniotic membrane is has a long history, first record of which dates back to 1934 (Brindeau, 1934)
Verbal consent only have been obtained from the patients who donated the amniotic membranes after their Cesarean delivery
Summary
Congenital absence (agenesis or atresia) of the vagina is encountered with a frequency of 1 in 4.000 to 5.000 (Raga et al, 1997). The treatment should provide an anatomically acceptable result from the viewpoint of the surgeon and a satifacory sexual experience on the part of the patient and the spouse/partner. This in turn involves the timing and the time length between the decision to have the condition treated and the onset of a satisfactory sexual life. In the review by Callens et al the analysis of 9 studies reporting Modified McIndoe procedure with amnion, 97% of the total patient sample resulted in normal gjhs.ccsenet.org. To assess the anatomical and functional results of neovagina creation with amniotic membrane
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