Amniotic fluid glucose at the time of genetic amniocentesis: correlation with duration of pregnancy and birthweight

Abstract

Objective: To test whether amniotic fluid (AF) glucose levels in 15–18 weeks of pregnancy can predict birthweight and duration of pregnancy. Study design: In this prospective study, 66 non-diabetic pregnant women underwent amniocentesis between 15 and 18 weeks of pregnancy and glucose levels were measured immediately by using the enzymatic method of hexocinase. They were all followed up and delivered in our department and neognological parameters were recorded. Results: AF glucose values ranged from 12 to 69 mg/dl (mean 44.2 mg/dl, S.D. 11.6 mg/dl). No linear relationship was found between AF glucose and either birthweight or duration of pregnancy. Conclusion: AF glucose values between 15 and 18 weeks of pregnancy did not correlate with either birthweight or duration of pregnancy. A single measurement of this value cannot be used for the prediction of the factors studied.