Amniotic band disruption sequence

Abstract

A disruption of limb vasculature after the period of embryonic development can result in structural anomalies. This disruption can be due to tangled strands of amnion that encircle embryonic structures, placental emboli or death of a monozygotic twin [1]. Up to 50% of cases have other congenital anomalies including cleft lip, cleft palate, and clubfoot deformity [2]. Hand and finger anomalies occur in up to 80%. Other abnormalities found with amniotic band syndrome include clubhands, cleft lip and/or cleft palate, and haemangioma. The incidence varies from 1 in 10000 to 1 in 15000 live births.