Abstract
Transceptors are nutrient transporters that act as receptors to regulate downstream signaling pathways. Ammonium transceptors regulate fungal morphology in response to limiting levels of ammonium, which is utilized as a nitrogen source. Few studies have addressed to what extent ammonium transceptors are conserved in pathogenic fungi. Plant and animal fungal pathogens undergo a variety of developmental transitions during infection, and work on some plant fungal pathogens establishes the importance of ammonium transporters during host infection [1, 2]. More widespread studies are needed to determine if ammonium transceptors have a general role in regulating the virulence of fungal pathogens.
Highlights
Transceptors are nutrient transporters that act as receptors to regulate downstream signaling pathways
Plant and animal fungal pathogens undergo a variety of developmental transitions during infection, and work on some plant fungal pathogens establishes the importance of ammonium transporters during host infection [1, 2]
More widespread studies are needed to determine if ammonium transceptors have a general role in regulating the virulence of fungal pathogens
Summary
Citation: van den Berg B, Lister S, Rutherford JC (2019) Ammonium transceptors: Novel regulators of fungal development. PLoS Pathog 15(11): e1008059. https://doi.org/10.1371/journal. ppat.1008059 Funding: SL was supported by a UK Biotechnology and Biological Sciences Research Council studentship (https://bbsrc.ukri.org). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Competing interests: The authors have declared that no competing interests exist.
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