Abstract

An efficient one-pot process was developed to synthesize 4<i>H</i>-chromene derivatives using a three-component reaction involving salicylaldehydes, cyclic 1,3-diketones, and thiols in an aqueous medium at room temperature. This protocol was accomplished using the inexpensive and readily available catalyst NH<sub>4</sub>Cl. The attractive features of this protocol are: use of inexpensive catalyst NH<sub>4</sub>Cl, good yields, and mild and environmentally benign reaction conditions.

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