Abstract
Based on cyclohexanol, aliphatic amines (diethylamine, dipropylamine, dibutylamine, dihexylamine), and formaldehyde, new Mannich bases have been synthesized. The reaction was carried out at a temperature of 78–80°C for 4–5 h in a benzene solution at an equimolar ratio of the starting components. The yield of compounds was 63–80%. The physicochemical data of the synthesized compounds were determined. The composition and structure of the target products were confirmed by elemental analysis, IR, 1H and 13C NMR spectroscopy. Their influence on the vital activity of sulfate-reducing bacteria (SRB) of the "Desulfovibrio desulfuricans" type at three concentrations (25; 50; 100 mg/l) was studied. The resulting compounds showed high bactericidal properties. 1% solutions of these compounds in isopropyl alcohol at a concentration of 100 mg/l showed a 100% bactericidal effect. Given that these aminomethoxy derivatives of cyclohexanol affect bacteria at very low concentrations, they can be proposed as effective inhibitors against sulfate reducing bacteria. Keywords: cyclohexanol, aliphatic amines, Mannich bases, sulfatereducing bacteria, inhibitor-bactericides, biocorrosion.
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