Abstract

Nephrotoxicity manifested by renal insufficiency is a well-known consequence of aminoglycoside administration in hospitalized patients. We report two cases of aminoglycoside-induced nephrotoxicity as manifested by proximal tubular dysfunction (Fanconi's syndrome). In the two patients reported, the tubular dysfunction occurred at the extremes of renal function. In both patients, tubular function returned to normal when the antibiotic was discontinued. Because of the widespread use of these antibiotics in the critically ill patient, it may be prudent to recognize this disorder when managing fluids, electrolytes, and nutrition.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.