Abstract
A series of propargylamine derivatives possessing bactericidal activity against sulfate-reducing bacteria has been synthesized on the basis of bicyclo[2.2.1]hept-5-ene-2-yl-methylamine. It has been shown that in the case of interaction of aminated norbornene with propargyl bromide, corresponding adducts of the norbornene series which contain a terminal acetylene bond and an amino group in the side chain are formed depending on the molar ratio. Synthesized N-propargylbicyclo[2.2.1]hept-5-ene-2-yl-methylamine is a very reactive compound and can participate in various reactions, in particular, by the amino group or the double bond, to form new derivatives. It has been found that all the synthesized substances at their concentration of 500 mg/L fully inhibit the growth of sulfate-reducing bacteria.
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