Abstract
Primary (AL) amyloidosis is a monoclonal gammopathy of systemic involvement.The involvement of the gastrointestinal tract is manifested by varied and nonspecific signs and symptoms, may present itself differently depending on their location, and clinically and endoscopically mimic other diseases of the digestive tract. The final diagnosis is established by histological examination.The authors present the case of a patient with lower gastrointestinal bleeding who presented several subepithelial hemorrhagic suffusions distributed across the colonic mucosa, as the initial manifestation of primary AL amyloidosis and Multiple myeloma. We emphasize the relevance of this case for its rarity and the endoscopic and histological iconography collected.
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