Abstract
Anti-Mullerian hormone (AMH) and stem cell factor (SCF) are cytokines secreted by granulosa cells (GCs), playing different roles in ovarian physiology. We have demonstrated that recombinant human (rh)AMH inhibits the expression of SCF in cultured human (h)GCs. Little is known about the molecular mechanisms by which AMH regulates SCF. Here we investigated if there is a correlation between serum and follicular fluid (FF) AMH and SCF concentrations, and we evaluated if AMH has a regulatory effect on SCF at the transcription and translational levels.
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