Amfizemli Hastalarda Amfizem Yaygınlığının Arter Kan Gazı, Solunum Fonksiyon Testi ve Hastaların Performanslarıyla Olan İlişkisi: Tanımlayıcı Klinik Araştırma

Abstract

Objective: In emphysema, changes such as decrease in the maximum expiratory air flow, excessive ventilation and air trapping occur. These changes affect the patients' exercise tolerance and effort capacities in the later period. Our purpose was to determine the relation between the prevalence of emphysema and patients' performance, the level of obstruction in the patients, the changes occurring in patients' artery blood gas (ABG) and other emphysema parameters. Material and Methods: A total of 55 consecutive patients with definite emphysema were included in the study. Patients' demographic and clinical characteristics were recorded. High resolution computed tomography (HRCT), pulmonary function tests, ABG measurement, patient performance evaluation and lung quantitative perfusion scintigraphy were performed to all patients. HRCT and visual emphysema score were used to determine the distribution and prevalence of emphysema. Results: Negative correlation coefficients were found between the emphysema scores and forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), FEV1/FVC, diffusing capacity of the lung for carbon monoxide, oxygen saturation percentage and 6 minutes walking test (6MWT) and positive correlation coefficients were found residual volume (RV), total lung capacity, partial carbon monoxide tension, Global Obstructive Lung Disease stage and Modified Medical Research Council (p<0.05). Conclusion: It was determined that among all the parameters, the strongest negative correlation was with the 6MWT, and the strongest positive correlation was with the RV. It was seen that in terms of the zones, the percentage of perfusion decreased as the emphysema scores increased.