Abstract

BackgroundAmeloblastomas are rarely found in pregnant women, with only two cases reported in the scientific literature. We report the first case of ameloblastoma in a pregnant woman in Brazil.Case presentationA 27-year-old white woman, 12-weeks pregnant, presented with a large mass in her right posterior mandible. Panoramic radiography revealed a lesion involving her mandibular right first molar with displacement of her mandibular right third molar and impairment of the mandibular bone base. The results of an incisional biopsy led to a diagnosis of acanthomatous ameloblastoma. We fixed Erich arch bars to both dental arches and performed an en-bloc resection surgery under general anesthesia for tumor removal. She was then treated by maxillomandibular rigid fixation with the installation of a 2.7 mm non-locking reconstruction plate. So far, she has presented no motor deficits, chewing difficulties, or relevant asymmetries. The tumor showed no recurrence after the first year (pregnancy period) and post-surgery radiographic follow-up revealed a reduction in the surgical area after osseous growth in the margins of the lesion. Although she displayed no systemic comorbidities that affected pregnancy, the fetus was born with alobar holoprosencephaly.ConclusionsThe possible influence of pregnancy hormones on the growth and development of tumors in general and ameloblastoma in particular, is still not explained in the literature. However, evidence reveals that the issue should be further studied. Although en-bloc resection surgery is considered a radical method of treatment, it is an effective alternative in ameloblastoma removal, presenting low rates of recurrence.

Highlights

  • Ameloblastomas are rarely found in pregnant women, with only two cases reported in the scientific literature

  • En-bloc resection surgery is considered a radical method of treatment, it is an effective alternative in ameloblastoma removal, presenting low rates of recurrence

  • We present a rare clinical case of ameloblastoma in a 27-year-old white pregnant woman, the first case reported in the Brazilian population

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Summary

Conclusions

The possible influence of pregnancy hormones on the growth and development of tumors, ameloblastoma, is not explained in the literature. After the results of the examination-ray, the dentist told me I had an injury on the bone of the right mandible and referred me to the center for dental specialties at Sobradinho Regional Hospital for a consultation with a specialist. The specialist dentist said it was an injury involving the right side of my jaw and that surgery would be necessary to remove it. He explained that the lesion was large and it would be removed with a part of the injured bone and teeth involved. The dentist explained the risks of not removing the lesion and told me what the best time during pregnancy to do the procedure was. The scar was along the skin folds of my neck, so it does not appear on my face

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