Abstract
Ameloblastic fibrodentinoma (AFD) is a rare odontogenic tumor composed of epithelial and mesenchymal odontogenic tissues, currently described as ameloblastic fibroma with dentin-like formation. A 13-year-old Black male presented with a painless swelling in the left posterior region of the mandible. Intraoral examination revealed an expansive lesion with a hard consistency, covered by normal mucosa. Panoramic radiography and computed tomography showed a well-circumscribed mixed osteolytic/osteoblastic lesion involving impacted teeth #36 and #38, as well as the absence of tooth #37. An excisional biopsy was performed, and histological analysis revealed ameloblastic epithelial strands and nests laid in a myxoid cell-rich stroma, together with extensive dentin-like tissue formation, resulting in a diagnosis of AFD. No recurrence was observed during 2 years of follow-up. Because AFD is a rare and controversial entity, it must be distinguished from other odontogenic lesions.
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