Abstract
Environmental contamination of pyrethroids is responsible for increasing oxidative stress in man and animals. The present study was aimed to investigate the ameliorative effects of �-tocopherol on different stress parameters in rats. Significant (p<0.05) increased catalase activity in cypermethrin treated rats is maintained normal by the supplementation of �-tocopherol. Significantly reduced (p<0.05) SODs and GSH-Px activity by cypermethrin treated rats and activity of these enzymes were comparable to control animals by �-tocopherol supplementation. Significantly reduced GSH and increased (p<0.05) lipid peroxidation were observed in both groups, cypermethrin alone and along with the �-tocopherol treated groups. Observations from the present study suggest that �-tocopherol supplementation plays a protective role in cypermethrin induced oxidative stress in rats and linseed oil is not suitable as a vehicle for �-tocopherol.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
