Abstract

Abstract The hyperglycaemia defines features of type 2 diabetes (T2DM), which is a real time problem and poses a significant economic burden on the globe and is spreading like an epidemic. Currently it affects 384 million people on the globe and this number is expected to reach 592 million in 2035 as reiterated by International Diabetes Federation (IDF). By improving the quality of diet and decreasing the intake of sugary foods T2DM can be treated. Fenugreek seeds powder in sachet form of 20 g/day used to treat type 2 diabetes mellitus as a natural supplement. Anthropometric parameters of height, weight, age and BMI of T2DM patient was also calculated. In this study patients from Rawalpindi and Islamabad region were selected for study purpose. Blood sugar levels such as fasting blood glucose (FBG), random blood glucose (RBG), and HbA1c of both the groups (treated and control) were taken at baseline, after one month and at the end of study. When fenugreek seeds were given to T2DM patients significant decrease in their glucose levels were seen after 30 and then 60 days of treatment.

Highlights

  • IntroductionHerbs are commonly used by the people for certain treatments due to their health benefits

  • Since ancient times, herbs are commonly used by the people for certain treatments due to their health benefits

  • Fenugreek seeds are well known for their nutritional benefits

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Summary

Introduction

Herbs are commonly used by the people for certain treatments due to their health benefits. Numerous herbs/ plants are used to treat T2DM that but fenugreek seeds (FGS) are considered to be more effective. Fenugreek (Trigonella foenum‐graecum) belongs to the family of fabacea and is generally known as “Methi Dana” which has been used in cooking and medicinal practices since antiquity. Medhika Methi, Trigonella, Birds Foot and fenugreek etc. Fenugreek seeds help in lowering of glucose levels in blood. FGS contains chemicals which have anti-diabetic activity like fiber, saponins, amino acids etc. Fiber such as galactomannan helps to decrease the sugar levels in blood by delaying the carbohydrates absorption. 4-hydroxyisoleucine (4HIL) is present in the seeds which stimulates the secretion of insulin in pancreas that helps to lower the glucose absorption Fiber such as galactomannan helps to decrease the sugar levels in blood by delaying the carbohydrates absorption. 4-hydroxyisoleucine (4HIL) is present in the seeds which stimulates the secretion of insulin in pancreas that helps to lower the glucose absorption

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