Abstract

Ameliorative Effect of Vitamin C against Monosodium Glutamate Induced Toxicity on Testes and Cauda Epididymal Sperm Reserves in Adult Male Albino Rats

Highlights

  • A variety of environmental chemicals, industrial pollutants and food additives have been implicated as causing harmful effects (Moore, 2003)

  • There was no significant difference of the mean values of the initial body weight between all the studied groups

  • Calcium ion influx into cells accompanies cell injury caused by a variety of stimuli, including oxidative stress and calcium appears to be involved in the production of reactive oxygen species (ROS)

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Summary

Introduction

A variety of environmental chemicals, industrial pollutants and food additives have been implicated as causing harmful effects (Moore, 2003). Monosodium glutamate (MSG) is a commonly used food enhancer which causes a wide range of endocrinal disorders including reduced fertility rate in both sexes. This work was carried out to study the possible ameliorative effect of vitamin C on monosodium glutamate induced testicular toxicity in adult male albino rats. Group IV (20 rats) was subdivided into two subgroups and received both MSG and vitamin C in their previous doses. Results: There was a significant increase in the body weight (p

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