Abstract
Ameliorative Effect of Dried Seed Extract of Prunus dulcis (Mill.) D.A. Webb var. amara (DC.) on Scopolamine-induced Memory Impairment in Rats
Highlights
Cognitive disorders include various factors as amnesia, difficulties in attention and Alzheimer’s disease and other neurologically disorders
The term Neuroapoptsis means dead of neurons, leads to dementia, abnormal behaviour, psychological changes which may even leads to death of the individuals.[1]
The collected seeds were firstly peeled off, with the help of blender convert it into powdered form, about 200 gm of powdered was subjected it into defatting with the help of petroleum ether and subjected to filter with the help of musclein cloth and filtrate cake was subjected to dried at 50 degree for 10 min in hot air oven in order to remove moisture and make it dry
Summary
Cognitive disorders include various factors as amnesia, difficulties in attention and Alzheimer’s disease and other neurologically disorders. Basic mechanism of neuro related disorder underlies with neuroapoptsis. The term Neuroapoptsis means dead of neurons, leads to dementia, abnormal behaviour, psychological changes which may even leads to death of the individuals.[1]. Neurodegenerative disorders include various disease like Parkinson’s, Huntington’s disease and precipitates Alzheimer’s disease (AD). AD is characterized by the deficits in memory and impairement of reasoning process.[2]. Various cause for improper function of cognition in healthy individuals include, degeneration of neurons in the brain, inflammation of neurons, change in receptor activity, improper regulation in neuro-transmitter like serotonin, adrenaline, acetylcholine, dopamine and NMDA[3] and excess production of Reactive oxygen species and imbalance in quenching of this free radicals.[4]
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