Abstract
Genetic mosaic analysis is a powerful technique to analyze the function of cells with varied genotypes in the same animal. By contrast, cell-lineage tracing allows the history of a cell's development to be uncovered. Zebrafish are uniquely suited to merge mosaic and cell lineage studies, and in this issue of Nature Methods, Russell Collins and colleagues present the first non-invasive method of generating temporally and spatially controlled mosaics in zebrafish1.
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