Abstract

Dementia and Alzheimer’s disease (AD) are global health crises, with most affected individuals living in low- or middle-income countries. While research into diagnostics and therapeutics remains focused exclusively on high-income populations, recent technological breakthroughs suggest that low-cost AD diagnostics may soon be possible. However, as this disease shifts onto those with the least financial and structural ability to shoulder its burden, it is incumbent on high-income countries to develop accessible AD healthcare. We argue that there is a scientific and ethical mandate to develop low-cost diagnostics that will not only benefit patients in low-and middle-income countries but the AD field as a whole.

Highlights

  • Dementia and Alzheimer’s disease (AD) are global health crises, with most affected individuals living in lowor middle-income countries

  • This disparity between the cost and prevalence of dementia in low- and middle-income countries (LMIC) is in part due to lower wage costs and a higher proportion of informal care work—between 2010 and 2015, the dementiarelated costs in LMIC increased by 63%; the amount spent on professional care did not change [3]

  • This suggests that as dementia incidence increases in LMIC there has not been a concomitant boost to the professional care economy, changes which would support diagnosis and management

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Summary

Introduction

Dementia and Alzheimer’s disease (AD) are global health crises, with most affected individuals living in lowor middle-income countries. Though dementia was once considered a disease affecting high-income countries (HIC), approximately 58% of cases are currently found in low- and This suggests that as dementia incidence increases in LMIC there has not been a concomitant boost to the professional care economy, changes which would support diagnosis and management.

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