Abstract

Normal dogs were treated with intravenous BCG on a doubling interval schedule previously found to be clinically effective. Alveolar macrophages retrieved from the treated dogs exhibited marked non-specific cytotoxic effects on normal and neoplastic allogeneic cells. This was not observed with alveolar macrophages from normal unstimulated dogs. The relevance of these findings to the therapy of pulmonary metastases is discussed.

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