Abstract

This study attempted to comprehensively assess the factors which impact upon the alveolar carbon monoxide (CO) levels of smokers. Baseline measures of alveolar carbon monoxide (CO), daily cigarette rate, the CO yield of the brand of cigarette smoked, and smoking topography were obtained from 60 individuals enrolled in a stop smoking clinic. The results indicated that two topography measures, i.e., the interpuff interval ( p < .01) and cigarette duration ( p < .05), the amount of time since the last cigarette ( p < .05), and a self-rated estimate of depth of inhalation ( p < .05) were significantly correlated with alveolar CO. A forward stepwise multiple regression analysis also yielded a three variable equation (interpuff interval, the CO yield of the brand of cigarette smoked, and daily cigarette rate) which was highly predictive of alveolar CO ( p < .001) and accounted for 36% of the total variance. These results support the arguments of Frederiksen and Martin (1979) that the CO levels of smokers are determined by a variety of factors in addition to daily cigarette rate.

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