Alternative Treatment Modality of Recurrent Central Giant Cell Granuloma in the Maxilla: Seven Year Follow-up Case Report

Abstract

Objectives: The aim of this unique report was to evaluate the long term outcome of an aggressive central giant cell granuloma (CGCG) lesion by using surgical removal and corticosteroid injection technique.CGCG is an uncommon benign bony lesion that occurs in the mandible and maxilla. Methods: A 14 year-old female was admitted to our clinic with a complaint of hard swelling in the left maxillary anterior vestibule cortex. The lesion was surgically removed by enucleation which was carried out under local anesthesia. Histological investigation revealed a diagnosis of central giant cell granuloma. Patient’s recovery was uneventful. During follow-up for eight months, the mass was opened and deep curettage was performed. After that, at same seance, corticosteroids was injected. The injection was repeated at the same rate once a week for 6 following weeks. Results: At the follow-up examination after seven years, lesion and left maxillary canine were stable and asymptomatic. There was no recurrence of lesion. Conclusion: Surgical removal combined with intralesional corticosteroid injection is a promising treatment approach for CGCG, and it can be suggested to reduce the recurrence of the lesion.