Abstract
Rheumatoid arthritis is an inflammatory disease autoimmune disorder that develops when our immune system attacks the tissues near joints due to the release of chemicals and enzymes. Although the exact pathogenesis of the disease has yet to be determined, studies indicate that cellular proliferation of synoviocytes results in pannus formation, which damages cartilages and bones. Recent research also supports the role of free radicals in the disease's pathogenesis. For rheumatoid arthritis treatment, a variety of anti-inflammatory and other types of drugs are available. However, long-term use of such types of pharmacological drugs is associated with serious side effects. As a result, herbal remedies, lifestyle, nutritional, probiotics, dietary and psychological interventions provide a rich source of anti-arthritic agents along with management of rheumatoid arthritis. This review focused on pathogenesis, treatments approaches for RA, mechanism of action, patents of marketed products. Tailored made approaches for arthritis management helps the scientists and researchers for finding newer leads, promotes growth and development of herbal industries, significantly improving health.
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