Abstract

The effect of cadmium, manganese and nickel on the levels of copper, manganese, iron and zinc in liver was studied in sham operated and partially hepatectomized rats, 72 hrs after metal administration. Partial hepatectomy produced significant increase in the level of zinc and decrease in the levels of copper, iron and manganese. The metabolic disposition of these essential micronutrients were significantly altered as a result of cadmium administration in both the groups. Manganese and nickel had little effect and only induced the level of zinc.

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