Abstract
Aim: The aim of the present study was to assess the effects of a hyperlipidic diet set before puberty in male Wistar rats’ gonadal weights and testicular functions. MethodsMales rats were used for the study, they were randomly distributed into 2 groups: Control Group (CG: standard diet (normolipidemic) and Intervention Group (IG: hyperlipidemic diet), after 7 days of experimentation, 3 rats were sacrificed per week, blood samples were collected and HDL, LDL levels and triglyceride were analyzed. Resultstriglyceride and HDL levels showed a consistent change over the weeks of the study. Photomicraphie of the testicles of Wistar rats in the hyperlipid diet group for the first week showed Sertoli cell hyperplasia, during the second week we showed significant testicular hypertrophy and in the fifth week hyperplasia of the seminal vesicle characterized by an increase in the number of glandular epithelial cells is showed. The proliferating epithelium may form papillary structures with supporting stroma and with extension into the glandular lumen and total absence of sperm cells. Conclusion: Obesity is associated with many metabolic abnormalities. It induce disorders of spermatogenesis.
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