Alterations in Left Atrial and Left Ventricular Myocardial Function in Mixed Aortic Valve Disease

Abstract

Patients with mixed aortic valve disease (MAVD), defined as combined moderate or greater aortic stenosis (AS) and moderate or greater aortic regurgitation, are known to have poorer outcomes compared to patients with isolated severe aortic stenosis. Previous studies examining left atrial (LA) and left ventricular (LV) myocardial function have demonstrated that patients with isolated severe AS have alterations in these parameters that affect their clinical outcomes. The impact of MAVD on LA and LV myocardial function is unknown.