Abstract
Purpose: To analyze the impact of different uropathogenic microorganisms on various sperm parameters those are generally used to determine male fertilizing potential. Method: The standard strains viz. Serratia marcescens, Klebsiella pneumoniae, Enterobacter aerogenes, Candida albicans, Proteus mirabilis, Streptococcus pyogenes, Klebsiella oxytoca were checked for their impact on sperm motility, viability, morphology, Mg++ ATPase activity and acrosome status of spermatozoa. Results: S. marcescens, K. pneumoniae, E. aerogenes compromised sperm motility via agglutination and C. albicans impaired motility without agglutination. Further, these strains could also reduce viability resulting in sperm death. These strains induced morphological defects in spermatozoa as evident by electron microscopic studies. Incubation of spermatozoa with these uropathogenic strains led to reduction in Mg2+ dependent ATPase activity and also resulted in premature acrosomal loss. On the other hand, P. mirabilis, S. pyogenes, K. oxytoca did not alter any of these parameters. Conclusion: It can be concluded from the present study that certain uropathogenic strains can induce detrimental effects on spermatozoon thereby reducing its fertilizing ability.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
