Abstract

SummaryLiver and plasma activities of malic dehydrogenase (MDH) and glutamicpyruvic transaminase (GPT) have been measured in adult, male rats made to swim for 2 hours either as a single, acute exercise or after repeated daily exercises (training). Acute exercise caused a significant increase of both liver and plasma MDH activity. Repeated exercise (training) caused an increased basal MDH activity in liver but not plasma; in the trained rat, a 2-hour swimming exercise did not elicit a further elevation of MDH activity in liver nor did it elicit an elevation in plasma. Neither acute nor repeated exercise caused any alteration in liver or plasma GPT activities. The possibility of using alterations in plasma MDH activity as a criterion of training is suggested.

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