Abstract
Objectives We compared nitrite, B-type natriuretic peptide (BNP), and cGMP levels in preeclamptic with those found in healthy pregnant. Methods We studied 21 healthy pregnant and 27 preeclamptic. Plasma cGMP and BNP levels were determined by ELISA. Nitrite levels were determined by chemiluminescence. Results Higher cGMP and BNP, and lower nitrite levels were found in preeclamptic versus healthy pregnant. Conclusions Altered cGMP levels reflect increased BNP levels and not impaired nitric oxide activity in preeclampsia.
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