Abstract
The cardiovascular protective and hypolipidemia effects of soybean oil were investigated in normocholesteremic rats. Diets were prepared and designed to contain 50 % of energy as carbohydrate, 35 % as fat, and 15 % as protein. Groups of six rats were each fed one of these diets, while a group was fed pelletized mouse chow which served as the control. A significant reduction (p < 0.05) was observed in the cholesterol, triglyceride, and low-density lipoprotein (LDL) levels of the soybean oil fed group. There was no significant alteration in the high-density lipoprotein (HDL) levels of all the groups. The studied atherogenic indices were significantly low in the soybean oil fed group compared to the other groups. These results indicate a protective effect of soybean oil against the development of cardiovascular disease as well as the hyperlipidemia that characterize obesity, hypertension, and diabetes mellitus.
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