Abstract

Adrenal adenomas are observed in up to 7% of the population and are predominantly non-functional, increased 18F-fluorodeoxyglucose (FDG) uptake is seen in only a small portion of them on 18F-FDG positron emission tomography/computed tomography (PET/CT) imaging. In this report, we present the sequential 18F-FDG PET/CT imaging findings of 2 patients with radiologically or pathologically confirmed adrenal adenomas who had severely altered 18F-FDG uptake patterns in adrenal lesions in different imaging studies of the same patient. In light of these findings, we wanted to highlight that evaluating adrenal adenomas as cross-sectional with semi-quantitative PET/CT parameters obtained from single imaging may cause misinterpretation.

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