Abstract
Complete blood cell (CBC) changes are directly or indirectly related to cancer and have not been reported in bitches with mammary tumors. The aim of this study was to evaluate CBC changes in 161 bitches with mammary tumors, and to correlate them with disease progression. Normocytic and normochromic anemia and neutrophilic leukocytosis were observed and correlated with disease stages III, IV and V. In conclusion, anemia and leukocytosis may be correlated with advanced stages of mammary tumors in bitches.
Highlights
As neoplasias em cães e gatos têm aumentado substancialmente nos últimos anos, assumindo grande importância clínica e epidemiológica
anemia and leukocytosis may be correlated with advanced stages of mammary tumors
III breast cancer patients treated with adjuvant doxorubicin
Summary
ANTONIO HENRIQUE CEREDA DA SILVA1, DANIELLA MATOS DA SILVA2, CRISTINA RAUEN RIBAS3, ROSANGELA LOCATELLI DITTRICH4, PETERSON TRICHES DORNBUSCH4, SIMONE DOMIT GUÉRIOS4. As alterações no hemograma estão direta ou indiretamente relacionadas com câncer e são pouco descritas em cadelas com neoplasia mamária. O objetivo deste estudo foi analisar as alterações hematológicas em 161 cadelas portadoras de neoplasia mamária e correlacionar à progressão da doença. As principais alterações hematológicas encontradas foram anemia normocítica e normocrômica e leucocitose neutrofílica, sendo ambas mais frequentes em cadelas em estádio avançado (III, IV ou V) da doença. Conclui-se que as alterações laboratoriais de anemia e leucocitose verificadas em cadelas com neoplasia mamária estão correlacionadas positivamente com o estádio avançado da doença
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