Abstract
Production of rat alpha-fetoprotein by transplantable ascites hepatoma was studied by radioimmunoassay method. alpha-Fetoprotein was detected in sera from rats bearing 22 out of 50 ascites hepatoma cell lines that were previously negative for the presence of alpha-fetoprotein by the Ouchterlony test. alpha-Fetoprotein was also detected with high prevalency in Morris hepatomas and sublines of Yoshida sarcoma by this assay system.
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