Abstract
To improve the physicochemical stability and aqueous solubility of carnosic acid (CA), a CA dissolved microemulsion (CA-ME) consisting of Tween 20 (22.5%), lecithin (4.5%), propylene glycol (PG, 9%), α-tocopherol (4%) and diwater (60%) was developed. The ME showed excellent storage, dilution, thermo- and photo-stability. Meanwhile, all the MEs had relatively low Newtonian viscosities and exhibited Newtonian behaviors over a wider range of shear rates, indicating that the MEs were discontinuous. Furthermore, an electrochemical method was used to evaluate the antioxidant activity of the MEs, the results indicated that chronoamperometry was feasible for discontinuous MEs to evaluate their antioxidant activity. In chronoamperometry, CA and α-tocopherol exhibited synergistic antioxidative effect in the ME system. Therefore, the CA-MEs developed here could be a potential for food industry to protect bioactive components.
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