Abstract
Although adrenergic agonists and antagonists have extensive clinical use, their effects on the intestinal absorption of amino acids have rarely been investigated. This work attempts to study the effect of epinephrine on the mucosal uptake of phenylalanine in the rat jejunum, using an in situ double perfusion technique that allows the intestine and its vasculature to be perfused simultaneously and respectively with the amino acid and the hormone and its antagonists. Epinephrine reduced, by about 30%, the mucosal transport of phenylalanine by activating alpha 1, alpha 2, and beta adrenergic receptors. The effect of the latter was not apparent however, until the alpha 2 receptors were blocked.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
