Abstract
1. 1. Maturation-related changes in alpha- and beta-adrenergic mechanisms of the aorta were investigated in 1 day, 1 week, 1 month and 4 month old rabbits and guinea-pigs. 2. 2. Aortic strips from newborn rabbits were equally as sensitive to phenylephrine as strips from the older rabbits. 3. 3. Aortic strips from newborn rabbits did not relax as well in response to isoproterenol as did the strips from adult rabbits, although relaxation to sodium nitrite was comparable in both groups. 4. 4. Aortic strips from 4 month old guinea-pigs had less sensitivity to phenylephrine than did the three younger age groups. 5. 5. Relaxing ability of newborn guinea-pig aorta to isoproterenol and sodium nitrite was equal to that of adult guinea-pig aorta.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
