Abstract
The genetic polymorphism of human alpha 2-HS-glycoprotein (AHSG) was analyzed in a sample of 736 native individuals from the three provinces of the Basque Autonomous Community (Guipúzcoa, Vizcaya and Alava). The Basque population shows the highest frequency of the allele AHSG*3 described to date in European populations. The same is not true for the frequency of allele AHSG*2, which fits well into the genocline described in Europe, in accordance with the adaptive hypothesis.
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