Abstract

Carbon dioxide from untreated and alloxanized rats was collected free of atmospheric CO 2 and then analyzed for its stable carbon isotope ( 13C 12C ) ratio. Alloxan induced diabetic rats expired CO 2 with a 13C 12C ratio less than that for CO 2 collected from untreated rats. The difference in 13C 12C ratios indicated that alloxanized rats oxidized more lipid than control rats since rat lipid has a 13C 12C ratio less than that of glycogen.

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