Abstract

Temporomandibular disorders (TMD) are a group of painful musculoskeletal conditions that have been associated with chronic exposure to stress. Allostatic load measures stress-related cumulative strain on multiple organ-systems, particularly on cardiovascular, metabolic, neuroendocrine and immunological systems. Due to the heterogeneity of TMD population, assessing allostatic load among TMD patients may facilitate diagnosis and treatment selection. The current study 1) used Ward hierarchical cluster analysis to sub-classify a group of National Institute of Dental and Craniofacial Research's Temporomandibular Joint Implant Registry and Repository (TIRR) participants (n= 98) who were diagnosed with TMD pain (i.e., arthralgia and/or myalgia based on Research Diagnostic Criteria for TMD); and 2) compared allostatic load between TMD clusters and 120 TIRR participants of non-TMD controls.

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