Abstract
SUMMARY Plastic implants were combined with epikeratophakia grafts on the primate cornea. Implants in intrastromal pockets survived but did not substantially increase refractive powers. When implants were placed simultaneously with lyophilized epikeratophakia grafts, necrosis and loss of the graft ensued. Alloplastic implants survived on the cornea only if the overlying tissue contained living keratocytes, i.e., fresh donor tissue grafted over the implant or established lyophilized grafts in which the peripheral scar was opened slightly and the implant slipped between the graft and the cornea. Advantages of easily replaced implants include the ability to accommodate changing refractive needs, as for infants with monocular aphakia.
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