Abstract
Standardized surgical defects, 7 mm in diameter, were made bilaterally in the region below the root apices of the mandibular third molars in 16 Java monkeys. Allogenic demineralized dentin was placed in the defects on the right side while the contralateral cavities received no implants and served as controls. The defects were allowed to heal for periods of between 1 week to 1 year. Histologic study revealed that the allogenic demineralized dentin implants were tolerated well and were gradually resorbed. These implants were both osteoinductive and osteoconductive and secured complete osseous healing with an intact outer contour. The control cavities exhibited incomplete osseous healing with persisting fibrous defects and a depression in the outer contour. These results suggest that allogenic demineralized dentin might come close to fulfilling the criteria of an ideal implant for jawbone defects.
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