Abstract
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an effective and sometimes the only curative therapy for patients with certain hematological diseases. Allo-HSCT has been practiced in China for approximately 30 years, and great improvements have been made within the past decade, particularly in fields such as the haploidentical HSCT system, strategies to overcome relapse and GVHD, and modified HSCT for elderly patients. This review will describe the current situation and provide a prospective of these unique aspects of Allo-HSCT in China.
Highlights
Allogeneic hematopoietic stem cell transplantation is an effective and sometimes the only curative therapy for patients with certain hematological diseases
Current status of Allo-Hematopoietic stem cell transplantation (HSCT) in China It has been more than thirty years since the first allogeneic bone marrow transplantation was successfully performed in China [1], and during the past decades, substantial progress has been made in the field of allogeneic hematopoietic stem cell transplantation
These data are quite different from those reported by the CIBMTR(Center for International Blood and Marrow Transplant Research), which show that autologous HSCT takes up 58% of the total HSCT cases and that unrelated donors comprise nearly half of all the allogeneic HSCT graft sources in the USA
Summary
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an effective and sometimes the only curative therapy for patients with certain hematological diseases. The initiation of multi-center clinical trials and advances in translational research are important for promoting progress in HSCT methods in China.
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